Anti-Integrin beta 5 (Polyclonal), ALEXA Fluor 594

Catalog number:	GENTAUR-58be605d60b18 Buy Now
Price:	489 €
Supplier:	Bioss Polyclonal Antibodies
Product name:	Anti-Integrin beta 5 (Polyclonal), ALEXA Fluor 594
Quantity:	100 microliters
Related search:	beta polyclonal gene cell bind nbsp extracellular

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Type:	Conjugated Primary Antibody
Conjugated with:	594, ALEXA FLUOR®
Host organism:	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide:	Integrin beta 5
Specificity:	This antibody reacts specifically with Integrin beta 5
Modification:	No modification has been applied to this antibody
Modification site:	None
Clonality:	Polyclonal Antibody
Clone:	Polyclonal Antibodies
Concentration:	1ug per 1ul
Antigen Source:	KLH conjugated synthetic peptide derived from human Integrin beta 5
Gene ID:	3693
Applications:	IF(IHC-P)
Applications with corresponding dilutions:	IF(IHC-P)(1:50-200)
Cross reactive species:	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details:	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information:	Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature, Due to their weak individual binding, Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function, Integrins are generally present in high concentrations at the cell surface, Integrins bind many different ligands including laminin, They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit, This integrin is found in a variety of cells in most normal tissue, This integrin mediates cell adhesion to vitronectin and also recognizes fibronectin when the integrin is activated, but, integrins need to cluster and bind in groups in order to effectively bind the ECM, they bind ligands with very low affinity, unlike most other cell surface receptors, Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces, The integrin subunit beta 5 has only been associated with the alpha v subunit to form the alpha v beta 5 heterodimer
Purification method:	Purified by Protein A
Storage:	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission:	590nm/617nm
Also known as:	Integrin beta 5 Polyclonal Antibody
Other name:	Anti-Integrin beta 5 Polyclonal
Advisory:	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties:	For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Group:	Polyclonals and antibodies
About:	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target:	Integrin beta 5
Short name:	Anti-Integrin beta 5 (Polyclonal) Fluor 594
Technique:	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label:	ALEXA
Alternative name:	ALEXA Fluor 594, antibody to-Integrin b 5 (polyclonal)
Alternative technique:	polyclonals
Identity:	6160
Gene:	ITGB5 | More about : ITGB5
Long gene name:	integrin subunit beta 5
Synonyms gene name:	beta 5 , integrin
Locus:	3q21, 2
Discovery year:	1991-07-30
GenBank acession:	J05633
Entrez gene record:	3693
Pubmed identfication:	2211615
RefSeq identity:	NM_002213
Classification:	Integrin beta subunits
Havana BLAST/BLAT:	OTTHUMG00000159432

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