| Long name: |
ALEXA FLUOR 594 Conjugated, Integrin beta 3 Polyclonal Antibody |
| Also known as: |
Anti-Integrin beta 3 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Integrin beta 3 |
| Specificity: |
This is a highly specific antibody against Integrin beta 3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
27-77/788 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Integrin beta 3 |
| Gene ID Number: |
3690 |
| Swiss Prot: |
P05106 |
| Tested applications: |
IF(ICC), IF(IHC-P) |
| Recommended dilutions: |
IF(ICC)(1:50-200), IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Fibrinogen binding enhances SELP expression in activated platelets (By similarity), Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen, In case of HIV-1 infection, Integrin alpha-IIb/beta-3 is a receptor for fibronectin, Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain, Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands, This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface, fibrinogen, fibronectin, laminin, matrix metalloproteinase-2, osteomodulin, osteopontin, plasminogen, prothrombin, prothrombin, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions, thrombospondin, thrombospondin and vitronectin, vitronectin and von Willebrand factor, Integrin alpha-V/beta-3 is a receptor for cytotactin |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NRIF3 HSU37139 TAP20 CENPR |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
Integrin beta 3 |
| Short name: |
Integrin beta 3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, Integrin b 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6157 |
| Gene: |
ITGB3BP |
More about : ITGB3BP |
| Long gene name: |
integrin subunit beta 3 binding protein |
| Synonyms gene name: |
integrin beta 3 binding protein (beta3-endonexin) |
| Synonyms name: |
centromere protein R beta3-endonexin |
| Locus: |
1p31, 3 |
| Discovery year: |
2000-05-08 |
| GenBank acession: |
U37139 |
| Entrez gene record: |
23421 |
| Pubmed identfication: |
7593198 10490654 |
| RefSeq identity: |
NM_014288 |
| Havana BLAST/BLAT: |
OTTHUMG00000013364 |