| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Integrin alpha 4/CD49d |
| Specificity: |
This antibody reacts specifically with Integrin alpha 4/CD49d |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Integrin alpha 4 |
| Gene ID: |
3676 |
| Swiss Prot: |
P13612 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rabbit, Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1, Integrin alpha-4/beta-7 is also a receptor for MADCAM1, It may also participate in cytolytic T-cell interactions with target cells, It recognizes the sequence L-D-T in MADCAM1, On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines, They are also receptors for VCAM1, They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin, Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CD49 antigen-like family member D, CD49D, ITGA4, Integrin alpha-4, Integrin alpha-IV, VLA-4 subunit alpha, IA4 |
| Also known as: |
Integrin alpha 4/CD49d Antibody |
| Other name: |
Anti-Integrin alpha 4/CD49d |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Integrin alpha 4/CD49d |
| Short name: |
Fluor 594, Anti-Integrin alpha 4/CD49d |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Integrin a 4/CD49d |