| Catalog number: | GENTAUR-58be605ce96f0 |
|---|---|
| Price: | 332 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | Anti-Integrin alpha 3 (Polyclonal), ALEXA Fluor 594 |
| Quantity: | 100ul |
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| Type: | Conjugated Primary Antibody |
|---|---|
| Conjugated with: | 594, ALEXA FLUOR® |
| Host organism: | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: | Integrin alpha 3 |
| Specificity: | This antibody reacts specifically with Integrin alpha 3 |
| Modification: | No modification has been applied to this antibody |
| Modification site: | None |
| Clonality: | Polyclonal Antibody |
| Clone: | Polyclonal Antibodies |
| Concentration: | 1ug per 1ul |
| Subcellular locations: | Transmembrane |
| Antigen Source: | KLH conjugated synthetic peptide derived from human Integrin alpha 3 |
| Gene ID: | 3675 |
| Swiss Prot: | P26006 |
| Applications: | IF(IHC-P) |
| Applications with corresponding dilutions: | IF(IHC-P)(1:50-200) |
| Cross reactive species: | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: | Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration, Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, collagen, epiligrin, formation of invadopodia and matrix degradation processes, laminin, promoting cell invasion, thrombospondin and CSPG4, Integrin alpha-3/beta-1 is a receptor for fibronectin |
| Purification method: | Purified by Protein A |
| Storage: | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: | 590nm/617nm |
| Synonyms: | CD49c VLA3a VCA-2 GAP-B3 |
| Also known as: | Integrin alpha 3 Polyclonal Antibody |
| Other name: | Anti-Integrin alpha 3 Polyclonal |
| Advisory: | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: | For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Group: | Polyclonals and antibodies |
| About: | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: | Integrin alpha 3 |
| Short name: | Anti-Integrin alpha 3 (Polyclonal) Fluor 594 |
| Technique: | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label: | ALEXA |
| Alternative name: | ALEXA Fluor 594, antibody to-Integrin a 3 (polyclonal) |
| Alternative technique: | polyclonals |
| Identity: | 6139 |
| Gene: | ITGA3 | More about : ITGA3 |
| Long gene name: | integrin subunit alpha 3 |
| Synonyms gene: | MSK18 |
| Synonyms gene name: | alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) , antigen identified by monoclonal antibody J143 integrin |
| Synonyms name: | alpha 3 subunit of VLA-3 receptor antigen CD49C |
| Locus: | 17q21, 33 |
| Discovery year: | 1992-02-27 |
| GenBank acession: | M59911 |
| Entrez gene record: | 3675 |
| Pubmed identfication: | 1655803 9704023 |
| RefSeq identity: | NM_005501 |
| Classification: | Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT: | OTTHUMG00000161890 |
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