Anti-Integrin beta 3 (Polyclonal), ALEXA Fluor 594

Catalog number:	GENTAUR-58be598496ad1 Buy Now
Price:	489 €
Supplier:	Bioss Polyclonal Antibodies
Product name:	Anti-Integrin beta 3 (Polyclonal), ALEXA Fluor 594
Quantity:	100 microliters
Related search:	integrin polyclonal gene protein alphaiibbeta nbsp receptor

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Type:	Conjugated Primary Antibody
Conjugated with:	594, ALEXA FLUOR®
Host organism:	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide:	Integrin beta 3
Specificity:	This antibody reacts specifically with Integrin beta 3
Modification:	No modification has been applied to this antibody
Modification site:	None
Clonality:	Polyclonal Antibody
Clone:	Polyclonal Antibodies
Concentration:	1ug per 1ul
Subcellular locations:	Extracellular
Antigen Source:	KLH conjugated synthetic peptide derived from human Integrin beta 3
Gene ID:	3690
Swiss Prot:	P05106
Applications:	IF(ICC), IF(IHC-P)
Applications with corresponding dilutions:	IF(ICC)(1:50-200), IF(IHC-P)(1:50-200)
Cross reactive species:	Mouse (Mus musculus), Human (Homo sapiens)
Cross Reactive Species details:	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information:	Fibrinogen binding enhances SELP expression in activated platelets (By similarity), Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen, In case of HIV-1 infection, Integrin alpha-IIb/beta-3 is a receptor for fibronectin, Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain, Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands, This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface, fibrinogen, fibronectin, laminin, matrix metalloproteinase-2, osteomodulin, osteopontin, plasminogen, prothrombin, prothrombin, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions, thrombospondin, thrombospondin and vitronectin, vitronectin and von Willebrand factor, Integrin alpha-V/beta-3 is a receptor for cytotactin
Purification method:	Purified by Protein A
Storage:	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission:	590nm/617nm
Synonyms:	NRIF3 HSU37139 TAP20 CENPR
Also known as:	Integrin beta 3 Polyclonal Antibody
Other name:	Anti-Integrin beta 3 Polyclonal
Advisory:	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties:	For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Group:	Polyclonals and antibodies
About:	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target:	Integrin beta 3
Short name:	Anti-Integrin beta 3 (Polyclonal) Fluor 594
Technique:	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label:	ALEXA
Alternative name:	ALEXA Fluor 594, antibody to-Integrin b 3 (polyclonal)
Alternative technique:	polyclonals
Identity:	6157
Gene:	ITGB3BP | More about : ITGB3BP
Long gene name:	integrin subunit beta 3 binding protein
Synonyms gene name:	integrin beta 3 binding protein (beta3-endonexin)
Synonyms name:	centromere protein R beta3-endonexin
Locus:	1p31, 3
Discovery year:	2000-05-08
GenBank acession:	U37139
Entrez gene record:	23421
Pubmed identfication:	7593198 10490654
RefSeq identity:	NM_014288
Havana BLAST/BLAT:	OTTHUMG00000013364

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