Anti-Claudin 1 (Polyclonal), ALEXA Fluor 594

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Catalog number: GENTAUR-58be5e48536a4
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: Anti-Claudin 1 (Polyclonal), ALEXA Fluor 594
Quantity: 100ul
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More details :

Type: Conjugated Primary Antibody
Conjugated with: 594, ALEXA FLUOR®
Host organism: Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide: Claudin 1
Specificity: This antibody reacts specifically with Claudin 1
Modification: No modification has been applied to this antibody
Modification site: None
Clonality: Polyclonal Antibody
Clone: Polyclonal Antibodies
Concentration: 1ug per 1ul
Subcellular locations: Cytoplasm
Antigen Source: KLH conjugated synthetic peptide derived from mouse Claudin 1
Gene ID: 12737
Swiss Prot: O88551
Applications: IF(IHC-P)
Applications with corresponding dilutions: IF(IHC-P)(1:50-200)
Cross reactive species: Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details: However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information: CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin, Often, Required for normal water homeostasis and to prevent excessive water loss through the skin, While some claudin family members play essential roles in the formation of impermeable barriers, and this determines the overall permeability, others mediate the permeability to ions and small molecules, probably via an indirect effect on the expression levels of other proteins, several claudin family members are coexpressed and interact with each other, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions, Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia
Purification method: Purified by Protein A
Storage: 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission: 590nm/617nm
Synonyms: SEMP1 ILVASC
Also known as: Claudin 1 Polyclonal Antibody
Other name: Anti-Claudin 1 Polyclonal
Advisory: For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties: For facs or microscopy Alexa 1 conjugate
Conjugation: Alexa Fluor
Group: Polyclonals and antibodies
About: The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target: Claudin 1
Short name: Anti-Claudin 1 (Polyclonal) Fluor 594
Technique: Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
Label: ALEXA
Alternative name: ALEXA Fluor 594, antibody to-Claudin 1 (polyclonal)
Alternative technique: polyclonals
Identity: 2032
Gene: CLDN1 | More about : CLDN1
Long gene name: claudin 1
Synonyms name: senescence-associated epithelial membrane protein 1
Locus: 3q28
Discovery year: 1998-11-19
GenBank acession: AF101051
Entrez gene record: 9076
Pubmed identfication: 10828592 9892664
RefSeq identity: NM_021101
Classification: Claudins
Havana BLAST/BLAT: OTTHUMG00000156214

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