Claudin 14 Antibody, ALEXA FLUOR 594

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Catalog number: bs-5025R-A594
Price: 489 €
Supplier: Bioss Polyclonal Antibodies
Product name: Claudin 14 Antibody, ALEXA FLUOR 594
Quantity: 100 microliters
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Long name: ALEXA FLUOR 594 Conjugated, Claudin 14 Polyclonal Antibody
Also known as: Anti-Claudin 14 PAb ALEXA FLUOR 594
Category: Conjugated Primary Antibodies
Conjugated with: 594, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: Claudin 14
Specificity: This is a highly specific antibody against Claudin 14
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Subcellular location: Extracellular
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Claudin 14
Tested applications: IF(IHC-P), FCM
Recommended dilutions: IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions, Claudin-14 is a multi-pass membrane protein that is expressed in liver, Claudins, Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues, Defects in the gene encoding claudin-14 are the cause of non-syndromic sensorineural deafness autosomal recessive type 29 (DFNB29), Occludin and Junction adhesion molecules, These proteins are important structural and functional components of tight junctions in paracellular transport, Three classes of proteins are known to localize to tight junctions, a form of hearing loss resulting from damage to either nerve pathways or neural receptors of the inner ear, including the claudins, kidney and ear, make up tight junction strands, which consist of four transmembrane domains and two extracellular loops, The Claudin superfamily consists of many structurally related proteins in humans
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 590nm/617nm
Properties: ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: 594, ALEXA FLUOR®, Alexa Fluor
Conjugated: Alexa conjugate 1
Gene target: Claudin 14
Short name: Claudin 14 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 594
Alternative name: ALEXA FLUOR 594, Claudin 14 (Antibody to)
Alternative technique: antibodies
Identity: 2035
Gene: CLDN14 | More about : CLDN14
Long gene name: claudin 14
Synonyms gene: DFNB29
Locus: 21q22, 13
Discovery year: 1999-11-26
GenBank acession: AJ132445
Entrez gene record: 23562
Pubmed identfication: 11163249
RefSeq identity: NM_144492
Classification: Claudins Deafness associated genes
Havana BLAST/BLAT: OTTHUMG00000086638
Locus Specific Databases: Hereditary Hearing Loss Homepage

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