Anti-Claudin 18 (Polyclonal), ALEXA Fluor 594

Catalog number:	GENTAUR-58be5e0e52b8d Buy Now
Price:	332 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	Anti-Claudin 18 (Polyclonal), ALEXA Fluor 594
Quantity:	100ul
Related search:	claudin polyclonal gene proteins junctions nbsp protein

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Type:	Conjugated Primary Antibody
Conjugated with:	594, ALEXA FLUOR®
Host organism:	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide:	Claudin 18
Specificity:	This antibody reacts specifically with Claudin 18
Modification:	No modification has been applied to this antibody
Modification site:	None
Clonality:	Polyclonal Antibody
Clone:	Polyclonal Antibodies
Concentration:	1ug per 1ul
Subcellular locations:	Extracellular
Antigen Source:	KLH conjugated synthetic peptide derived from human Claudin 18
Applications:	IF(IHC-P)
Applications with corresponding dilutions:	IF(IHC-P)(1:50-200)
Cross reactive species:	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details:	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information:	Claudins, Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues (1), Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge (5), Occludin and Junction adhesion molecule (3), These proteins are important structural and functional components of tight junctions in paracellular transport (1, Three classes of proteins are known to localize to tight junctions, including the Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands (4), 2), Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions (6), The Claudin superfamily consists of many structurally related proteins in humans (1)
Purification method:	Purified by Protein A
Storage:	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission:	590nm/617nm
Also known as:	Claudin 18 Polyclonal Antibody
Other name:	Anti-Claudin 18 Polyclonal
Advisory:	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties:	For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Group:	Polyclonals and antibodies
About:	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target:	Claudin 18
Short name:	Anti-Claudin 18 (Polyclonal) Fluor 594
Technique:	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label:	ALEXA
Alternative name:	ALEXA Fluor 594, antibody to-Claudin 18 (polyclonal)
Alternative technique:	polyclonals
Identity:	2039
Gene:	CLDN18 | More about : CLDN18
Long gene name:	claudin 18
Synonyms gene:	SFTPJ
Synonyms gene name:	surfactant associated protein J
Locus:	3q22, 3
Discovery year:	2000-01-31
GenBank acession:	AF221069 AY102073
Entrez gene record:	51208
RefSeq identity:	NM_001002026
Classification:	Claudins
Havana BLAST/BLAT:	OTTHUMG00000159762

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