HER2 (Tyr1221) Antibody, ALEXA FLUOR 594

Catalog number:	bs-13090R-A594 Buy Now
Price:	332 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	HER2 (Tyr1221) Antibody, ALEXA FLUOR 594
Quantity:	100ul
Related search:	alexa gene antibody erbb homolog tyrosine ligand

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Long name:	ALEXA FLUOR 594 Conjugated, HER2 (Tyr1221) Polyclonal Antibody
Also known as:	Anti-HER2 Tyr1221 PAb ALEXA FLUOR 594
Category:	Conjugated Primary Antibodies
Conjugated with:	594, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	HER2 Tyr1221
Specificity:	This is a highly specific antibody against HER2 Tyr1221
Modification:	Phosphorylation
Modification Site:	Tyr1221
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human HER2 around the phosphorylation site of Tyr1221
Gene ID Number:	2064
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, Alternative splicing results in several additional transcript variants, Amplification and/or overexpression of this gene has been reported in numerous cancers, However, Ile654/Ile655, Jul 2008], This protein has no ligand binding domain of its own and therefore cannot bind growth factors, [provided by RefSeq, including breast and ovarian tumors, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, shown here, some encoding different isoforms and others that have not been fully characterized, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase, with the most common allele, This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	590nm/617nm
Synonyms:	NEU HER-2 CD340 HER2
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	594, ALEXA FLUOR®, Alexa Fluor
Conjugated:	Alexa conjugate 1
Gene target:	HER2 (Tyr1221)
Short name:	HER2 (Tyr1221) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 594
Alternative name:	ALEXA FLUOR 594, HER2 (Tyr1221) (Antibody to)
Alternative technique:	antibodies
Identity:	3430
Gene:	ERBB2 | More about : ERBB2
Long gene name:	erb-b2 receptor tyrosine kinase 2
Synonyms gene:	NGL
Synonyms gene name:	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog) v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
Synonyms name:	neuro/glioblastoma derived oncogene homolog human epidermal growth factor receptor 2
Locus:	17q12
Discovery year:	2001-06-22
GenBank acession:	X03363
Entrez gene record:	2064
RefSeq identity:	NM_004448
Classification:	CD molecules Minor histocompatibility antigens Erb-b2 receptor tyrosine kinases
Havana BLAST/BLAT:	OTTHUMG00000179300
Locus Specific Databases:	LRG_724

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