HER2 (Tyr1221) Antibody, Cy5 Conjugated

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Catalog number: bs-13090R-Cy5
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: HER2 (Tyr1221) Antibody, Cy5 Conjugated
Quantity: 0.1ml
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More details :

Long name: Cy5 Conjugated, HER2 (Tyr1221) Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: 5, Cy5
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: HER2 Tyr1221
Specificity: This is a highly specific antibody against HER2 Tyr1221
Modification: Phosphorylation
Modification site: Tyr1221
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic phosphopeptide derived from human HER2 around the phosphorylation site of Tyr1221
Gene ID number: 2064
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, Alternative splicing results in several additional transcript variants, Amplification and/or overexpression of this gene has been reported in numerous cancers, However, Ile654/Ile655, Jul 2008], This protein has no ligand binding domain of its own and therefore cannot bind growth factors, [provided by RefSeq, including breast and ovarian tumors, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, shown here, some encoding different isoforms and others that have not been fully characterized, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase, with the most common allele, This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission: 625, 650nm/670nm
Synonyms: NEU HER-2 CD340 HER2
Properties: Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target: HER2 (Tyr1221) Conjugated
Short name: Conjugated, HER2 (Tyr1221) Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: Cy5
Alternative name: cyanine 5 coupled, HER2 (Tyr1221) (Antibody to)
Alternative technique: antibodies
Identity: 3430
Gene: ERBB2 | More about : ERBB2
Long gene name: erb-b2 receptor tyrosine kinase 2
Synonyms gene: NGL
Synonyms gene name: v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog) v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
Synonyms name: neuro/glioblastoma derived oncogene homolog human epidermal growth factor receptor 2
Locus: 17q12
Discovery year: 2001-06-22
GenBank acession: X03363
Entrez gene record: 2064
RefSeq identity: NM_004448
Classification: CD molecules Minor histocompatibility antigens Erb-b2 receptor tyrosine kinases
Havana BLAST/BLAT: OTTHUMG00000179300
Locus Specific Databases: LRG_724

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