| Catalog number: | bs-13090R-HRP |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | HER2 (Tyr1221) Antibody, HRP Conjugated |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | HRP Conjugated, HER2 (Tyr1221) Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | HRP Conjugated |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | HER2 Tyr1221 |
| Specificity: | This is a highly specific antibody against HER2 Tyr1221 |
| Modification: | Phosphorylation |
| Modification site: | Tyr1221 |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic phosphopeptide derived from human HER2 around the phosphorylation site of Tyr1221 |
| Gene ID number: | 2064 |
| Tested applications: | IHC-P, WB |
| Recommended dilutions: | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: | Mouse, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, Alternative splicing results in several additional transcript variants, Amplification and/or overexpression of this gene has been reported in numerous cancers, However, Ile654/Ile655, Jul 2008], This protein has no ligand binding domain of its own and therefore cannot bind growth factors, [provided by RefSeq, including breast and ovarian tumors, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, shown here, some encoding different isoforms and others that have not been fully characterized, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase, with the most common allele, This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: | NEU HER-2 CD340 HER2 |
| Properties: | Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase  |
| Gene target: | HER2 (Tyr1221) Conjugated |
| Short name: | Conjugated, HER2 (Tyr1221) Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | HRP |
| Alternative name: | horseradish peroxidase coupled, HER2 (Tyr1221) (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 3430 |
| Gene: | ERBB2 | More about : ERBB2 |
| Long gene name: | erb-b2 receptor tyrosine kinase 2 |
| Synonyms gene: | NGL |
| Synonyms gene name: | v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog) v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 |
| Synonyms name: | neuro/glioblastoma derived oncogene homolog human epidermal growth factor receptor 2 |
| Locus: | 17q12 |
| Discovery year: | 2001-06-22 |
| GenBank acession: | X03363 |
| Entrez gene record: | 2064 |
| RefSeq identity: | NM_004448 |
| Classification: | CD molecules Minor histocompatibility antigens Erb-b2 receptor tyrosine kinases |
| Havana BLAST/BLAT: | OTTHUMG00000179300 |
| Locus Specific Databases: | LRG_724 |
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