HER2 (Tyr1221) Antibody, Cy3 Conjugated

Catalog number:	bs-13090R-Cy3 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	HER2 (Tyr1221) Antibody, Cy3 Conjugated
Quantity:	0.1ml
Related search:	antibody her gene antibodies erbb this homolog ligand

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Long name:	Cy3 Conjugated, HER2 (Tyr1221) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	cy3 conjugation kit
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	HER2 Tyr1221
Specificity:	This is a highly specific antibody against HER2 Tyr1221
Modification:	Phosphorylation
Modification site:	Tyr1221
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human HER2 around the phosphorylation site of Tyr1221
Gene ID number:	2064
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, Alternative splicing results in several additional transcript variants, Amplification and/or overexpression of this gene has been reported in numerous cancers, However, Ile654/Ile655, Jul 2008], This protein has no ligand binding domain of its own and therefore cannot bind growth factors, [provided by RefSeq, including breast and ovarian tumors, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, shown here, some encoding different isoforms and others that have not been fully characterized, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase, with the most common allele, This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	512, 550nm/570, 615nm
Synonyms:	NEU HER-2 CD340 HER2
Properties:	1 of the HER2 (Tyr1221) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	HER2 (Tyr1221) Conjugated
Short name:	Conjugated, HER2 (Tyr1221) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy3
Alternative name:	cyanine 3 coupled, HER2 (Tyr1221) (Antibody to)
Alternative technique:	antibodies
Identity:	3430
Gene:	ERBB2 | More about : ERBB2
Long gene name:	erb-b2 receptor tyrosine kinase 2
Synonyms gene:	NGL
Synonyms gene name:	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog) v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
Synonyms name:	neuro/glioblastoma derived oncogene homolog human epidermal growth factor receptor 2
Locus:	17q12
Discovery year:	2001-06-22
GenBank acession:	X03363
Entrez gene record:	2064
RefSeq identity:	NM_004448
Classification:	CD molecules Minor histocompatibility antigens Erb-b2 receptor tyrosine kinases
Havana BLAST/BLAT:	OTTHUMG00000179300
Locus Specific Databases:	LRG_724

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