Exportin 1/CRM1 Antibody, ALEXA FLUOR 555

Catalog number:	bs-10151R-A555 Buy Now
Price:	819 €
Supplier:	acr
Product name:	Exportin 1/CRM1 Antibody, ALEXA FLUOR 555
Quantity:	50 Вµg
Related search:	crm exportin antibody export nuclear conjugated complex yeast rex

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Long name:	ALEXA FLUOR 555 Conjugated, Exportin 1/CRM1 Polyclonal Antibody
Also known as:	Anti-Exportin 1/CRM1 PAb ALEXA FLUOR 555
Category:	Conjugated Primary Antibodies
Conjugated with:	555, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Exportin 1/CRM1
Specificity:	This is a highly specific antibody against Exportin 1/CRM1
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	720-770/1071
Subcellular location:	Cytoplasm
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Exportin 1/CRM1
Gene ID Number:	7514
Swiss Prot:	O14980
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Binds to late precursor U3 snoRNA bearing a TMG cap, Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins, HTLV-1 and influenza A use it to export their unspliced or incompletely spliced RNAs out of the nucleus, In the nucleus, Interacts with, Involved in HTLV-1 Rex multimerization, Involved in U3 snoRNA transport from Cajal bodies to nucleoli, Several viruses, The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus, Upon transit of a nuclear export complex into the cytoplasm, among them HIV-1, and mediates the nuclear export of HIV-1 Rev and HTLV-1 Rex proteins, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP), disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, in association with RANBP3, respectively) cause release of the cargo from the export receptor, Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	553nm/568nm
Synonyms:	CRM1 emb
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 555, Alexa Fluor
Gene target:	Exportin 1/CRM1
Short name:	Exportin 1/CRM1 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 555
Alternative name:	ALEXA FLUOR 555, Exportin 1/CRM1 (Antibody to)
Alternative technique:	antibodies
Identity:	12825
Gene:	XPO1 | More about : XPO1
Long gene name:	exportin 1
Synonyms gene name:	exportin 1 (CRM1, homolog) exportin 1 (CRM1 homolog, yeast, yeast)
Synonyms name:	chromosome region maintenance 1 homolog (yeast)
Locus:	2p15
Discovery year:	1998-05-12
GenBank acession:	Y08614
Entrez gene record:	7514
Pubmed identfication:	9205132 9368044
RefSeq identity:	NM_003400
Classification:	Exportins
Havana BLAST/BLAT:	OTTHUMG00000152316

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