Exportin 1/CRM1 Antibody, Cy7 Conjugated

Catalog number:	bs-10151R-Cy7 Buy Now
Price:	587 €
Supplier:	acr
Product name:	Exportin 1/CRM1 Antibody, Cy7 Conjugated
Quantity:	0,4 ml
Related search:	crm antibody export nuclear complex yeast ran

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Long name:	Cy7 Conjugated, Exportin 1/CRM1 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Cy7
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Exportin 1/CRM1
Specificity:	This is a highly specific antibody against Exportin 1/CRM1
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	720-770/1071
Subcellular location:	Cytoplasm
Source:	KLH conjugated synthetic peptide derived from human Exportin 1/CRM1
Gene ID number:	7514
Swiss Prot:	O14980
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Binds to late precursor U3 snoRNA bearing a TMG cap, Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins, HTLV-1 and influenza A use it to export their unspliced or incompletely spliced RNAs out of the nucleus, In the nucleus, Interacts with, Involved in HTLV-1 Rex multimerization, Involved in U3 snoRNA transport from Cajal bodies to nucleoli, Several viruses, The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus, Upon transit of a nuclear export complex into the cytoplasm, among them HIV-1, and mediates the nuclear export of HIV-1 Rev and HTLV-1 Rex proteins, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP), disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, in association with RANBP3, respectively) cause release of the cargo from the export receptor, Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	743nm/767nm
Synonyms:	CRM1 emb
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated:	These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene target:	Exportin 1/CRM1 Conjugated
Short name:	Conjugated, Exportin 1/CRM1 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy7
Alternative name:	cyanine 7 coupled, Exportin 1/CRM1 (Antibody to)
Alternative technique:	antibodies
Identity:	12825
Gene:	XPO1 | More about : XPO1
Long gene name:	exportin 1
Synonyms gene name:	exportin 1 (CRM1, homolog) exportin 1 (CRM1 homolog, yeast, yeast)
Synonyms name:	chromosome region maintenance 1 homolog (yeast)
Locus:	2p15
Discovery year:	1998-05-12
GenBank acession:	Y08614
Entrez gene record:	7514
Pubmed identfication:	9205132 9368044
RefSeq identity:	NM_003400
Classification:	Exportins
Havana BLAST/BLAT:	OTTHUMG00000152316

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• #antibody
• #export
• #nuclear
• #complex
• #yeast
• #ran