| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CRM1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (FFPE): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the CRM1 antibody should be determined by the researcher |
| Intented use: |
This CRM1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O14980 |
| Purity: |
Antigen affinity |
| Description: |
Additionally, It also regulates NFAT and AP-1, It specifically inhibits the nuclear export of Rev and U snRNAs, MPAK, This protein mediates leucine-rich nuclear export signal (NES)-dependent protein transport, also known as chromosomal maintenance 1 (CRM1), and MAPKAP kinase 2, is an eukaryotic protein that mapped to human chromosome 2p16 by fluorescence in situ hybridization, this protein is involved in the control of several cellular processes by controlling the localization of cyclin B, Exportin 1 (XPO1) |
| Immunogen: |
Amino acids N966-D1071 from the human protein were used as the immunogen for the CRM1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CRM1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Nuclear |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CRM1 |
| Short name: |
CRM1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CRM1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12825 |
| Gene: |
XPO1 |
More about : XPO1 |
| Long gene name: |
exportin 1 |
| Synonyms gene name: |
exportin 1 (CRM1, homolog) exportin 1 (CRM1 homolog, yeast, yeast) |
| Synonyms: |
CRM1 emb |
| Synonyms name: |
chromosome region maintenance 1 homolog (yeast) |
| Locus: |
2p15 |
| Discovery year: |
1998-05-12 |
| GenBank acession: |
Y08614 |
| Entrez gene record: |
7514 |
| Pubmed identfication: |
9205132 9368044 |
| RefSeq identity: |
NM_003400 |
| Classification: |
Exportins |
| Havana BLAST/BLAT: |
OTTHUMG00000152316 |