| Catalog number: | bs-0110R-Cy7 |
|---|---|
| Price: | 368 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | FE65 Antibody, Cy7 Conjugated |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | Cy7 Conjugated, FE65 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Cy7 |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | FE65 |
| Specificity: | This is a highly specific antibody against FE65 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen_range: | 225-265/710 |
| Subcellular location: | Cell membrane, Nucleus, Cytoplasm |
| Source: | KLH conjugated synthetic peptide derived from human Fe65 protein |
| Gene ID number: | 322 |
| Swiss Prot: | O00213 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Adapter protein that forms a transcriptionally active complex with the gamma-secretase-derived amyloid precursor protein (APP) intracellular domain, Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s), Function in association with TSHZ3, Its ability to specifically bind modified histones and chromatin modifying enzymes such as KAT5/TIP60, May act by specifically recognizing and binding histone H2AX phosphorylated on 'Tyr-142' (H2AXY142ph) at double-strand breaks (DSBs), Plays a central role in the response to DNA damage by translocating to the nucleus and inducing apoptosis, Required for histone H4 acetylation at double-strand breaks (DSBs), SET and HDAC factors as a transcriptional repressor, probably explains its trancription activation activity, recruiting other pro-apoptosis factors such as MAPK8/JNK1, that inhibits the expression of CASP4, Transcription coregulator that can have both coactivator and corepressor functions |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 743nm/767nm |
| Synonyms: | Fe65 |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: | FE65 Conjugated |
| Short name: | Conjugated, FE65 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Cy7 |
| Alternative name: | cyanine 7 coupled, FE65 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 581 |
| Gene: | APBB1 | More about : APBB1 |
| Long gene name: | amyloid beta precursor protein binding family B member 1 |
| Synonyms gene: | RIR |
| Synonyms gene name: | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| Locus: | 11p15, 4 |
| Discovery year: | 1997-03-27 |
| GenBank acession: | L77864 |
| Entrez gene record: | 322 |
| Pubmed identfication: | 8955346 8894693 |
| RefSeq identity: | NM_001164 |
| Havana BLAST/BLAT: | OTTHUMG00000165454 |
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