| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
FE65 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the FE65 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This FE65 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
322 |
| Purity: |
Antigen affinity |
| Description: |
APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation, Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression, It interacts with the Alzheimers disease amyloid precursor protein (APP), It is an adaptor protein localized in the nucleus, It is thought to regulate transcription, Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene, The protein encoded by this gene is a member of the Fe65 protein family, This encoded protein could play an important role in the pathogenesis of Alzheimers disease, transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein, APBB1 is also known as RIR or FE65 |
| Immunogen: |
Human partial recombinant protein (AA 295-613) was used as the immunogen for this FE65 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the FE65 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
FE65 |
| Short name: |
FE65 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FE65 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
581 |
| Gene: |
APBB1 |
More about : APBB1 |
| Long gene name: |
amyloid beta precursor protein binding family B member 1 |
| Synonyms gene: |
RIR |
| Synonyms gene name: |
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| Synonyms: |
Fe65 |
| Locus: |
11p15, 4 |
| Discovery year: |
1997-03-27 |
| GenBank acession: |
L77864 |
| Entrez gene record: |
322 |
| Pubmed identfication: |
8955346 8894693 |
| RefSeq identity: |
NM_001164 |
| Havana BLAST/BLAT: |
OTTHUMG00000165454 |