FE65 Antibody, ALEXA FLUOR 350

Catalog number:	bs-0110R-A350 Buy Now
Price:	332 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	FE65 Antibody, ALEXA FLUOR 350
Quantity:	100ul
Related search:	alexa antibody gene antibodies protein synonyms year

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Long name:	ALEXA FLUOR 350 Conjugated, FE65 Polyclonal Antibody
Also known as:	Anti-FE65 PAb ALEXA FLUOR 350
Category:	Conjugated Primary Antibodies
Conjugated with:	350, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	FE65
Specificity:	This is a highly specific antibody against FE65
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	225-265/710
Subcellular location:	Cell membrane, Nucleus, Cytoplasm
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fe65 protein
Gene ID Number:	322
Swiss Prot:	O00213
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Adapter protein that forms a transcriptionally active complex with the gamma-secretase-derived amyloid precursor protein (APP) intracellular domain, Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s), Function in association with TSHZ3, Its ability to specifically bind modified histones and chromatin modifying enzymes such as KAT5/TIP60, May act by specifically recognizing and binding histone H2AX phosphorylated on 'Tyr-142' (H2AXY142ph) at double-strand breaks (DSBs), Plays a central role in the response to DNA damage by translocating to the nucleus and inducing apoptosis, Required for histone H4 acetylation at double-strand breaks (DSBs), SET and HDAC factors as a transcriptional repressor, probably explains its trancription activation activity, recruiting other pro-apoptosis factors such as MAPK8/JNK1, that inhibits the expression of CASP4, Transcription coregulator that can have both coactivator and corepressor functions
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	343nm/442nm
Synonyms:	Fe65
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 350, Alexa Fluor
Gene target:	FE65
Short name:	FE65 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 350
Alternative name:	ALEXA FLUOR 350, FE65 (Antibody to)
Alternative technique:	antibodies
Identity:	581
Gene:	APBB1 | More about : APBB1
Long gene name:	amyloid beta precursor protein binding family B member 1
Synonyms gene:	RIR
Synonyms gene name:	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
Locus:	11p15, 4
Discovery year:	1997-03-27
GenBank acession:	L77864
Entrez gene record:	322
Pubmed identfication:	8955346 8894693
RefSeq identity:	NM_001164
Havana BLAST/BLAT:	OTTHUMG00000165454

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