| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FE65 |
| Specificity: |
This antibody reacts specifically with FE65 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Fe65 protein |
| Gene ID: |
322 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation, Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression, It interacts with the Alzheimer's disease amyloid precursor protein (APP), It is an adaptor protein localized in the nucleus, It is thought to regulate transcription, Mar 2012], Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene, This encoded protein could play an important role in the pathogenesis of Alzheimer's disease, [provided by RefSeq, transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein, The protein encoded by this gene is a member of the Fe65 protein family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Fe65 |
| Also known as: |
FE65 Polyclonal Antibody |
| Other name: |
Anti-FE65 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FE65 |
| Short name: |
Anti-FE65 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FE65 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
581 |
| Gene: |
APBB1 |
More about : APBB1 |
| Long gene name: |
amyloid beta precursor protein binding family B member 1 |
| Synonyms gene: |
RIR |
| Synonyms gene name: |
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| Locus: |
11p15, 4 |
| Discovery year: |
1997-03-27 |
| GenBank acession: |
L77864 |
| Entrez gene record: |
322 |
| Pubmed identfication: |
8955346 8894693 |
| RefSeq identity: |
NM_001164 |
| Havana BLAST/BLAT: |
OTTHUMG00000165454 |