| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FOXD |
| Specificity: |
2, 3 and 4, Pan FOXD, This antibody is useful for detecting the total expression level FOXD1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FOXD1 |
| Gene ID: |
2297, 2298, 2306, 27022 |
| Swiss Prot: |
Q16676 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also acts as a transcriptional activator, Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor, Can neuralize ectodermal cells directly By similarity, Deficiency of FOXD1 results in multiorgan systemic inflammation, Deletion of FOXD1 results in renal abnormalities, FOXD1 controls the production of signals required for the normal transition of induced mesenchyme into tubular epithelium and full growth and branching of the collecting system, FOXD1 is involved in regulating inflammation as well as kidney and retinal development, FOXD1 regulates the activity of NFAT and NFkB, FOXD2 acts as a modulator of T cell activation, In kidneys, Probable transcription factor involved in embryogenesis and somatogenesis, Promotes development of neural crest cells from neural tube progenitors, Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis, Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation, and T cell proliferation in autogolgous MLRs, exaggerated Th cell-derived cytokine production, regionalization of the optic chiasm and morphogenesis of the kidney, Transcription factor required for formation of positional identity in the developing retina |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FOXD1Forkhead box protein D4, FOXD3, FREAC-4Forkhead box protein D2, FREAC-5, FREAC-9, Forkhead-related protein FKHL17, Forkhead-related protein FKHL8, Forkhead-related protein FKHL9, Forkhead-related transcription factor 4, Forkhead-related transcription factor 5, Forkhead-related transcription factor 9, HNF3/FH transcription factor genesis, Forkhead box protein D1 |
| Also known as: |
Pan FOXD Polyclonal Antibody |
| Other name: |
Anti- Pan FOXD Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Pan FOXD |
| Short name: |
Anti- Pan FOXD (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, Antibody to Pan FOXD (polyclonal) |
| Alternative technique: |
polyclonals |