| Long name: |
ALEXA FLUOR 488 Conjugated, Pan FOXD Polyclonal Antibody |
| Also known as: |
Anti-FOXD PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FOXD |
| Specificity: |
This is a highly specific antibody against FOXD |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
140-190/465 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FOXD1 |
| Gene ID Number: |
2297, 2298, 2306, 27022 |
| Swiss Prot: |
Q16676 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Also acts as a transcriptional activator, Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor, Can neuralize ectodermal cells directly By similarity, Deficiency of FOXD1 results in multiorgan systemic inflammation, Deletion of FOXD1 results in renal abnormalities, FOXD1 controls the production of signals required for the normal transition of induced mesenchyme into tubular epithelium and full growth and branching of the collecting system, FOXD1 is involved in regulating inflammation as well as kidney and retinal development, FOXD1 regulates the activity of NFAT and NFkB, FOXD2 acts as a modulator of T cell activation, In kidneys, Probable transcription factor involved in embryogenesis and somatogenesis, Promotes development of neural crest cells from neural tube progenitors, Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis, Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation, and T cell proliferation in autogolgous MLRs, exaggerated Th cell-derived cytokine production, regionalization of the optic chiasm and morphogenesis of the kidney, Transcription factor required for formation of positional identity in the developing retina |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
FOXD1Forkhead box protein D4, FOXD3, FREAC-4Forkhead box protein D2, FREAC-5, FREAC-9, Forkhead-related protein FKHL17, Forkhead-related protein FKHL8, Forkhead-related protein FKHL9, Forkhead-related transcription factor 4, Forkhead-related transcription factor 5, Forkhead-related transcription factor 9, HNF3/FH transcription factor genesis, Forkhead box protein D1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Pan FOXD Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Pan FOXD |
| Short name: |
Pan FOXD Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Pan FOXD (Antibody to) |
| Alternative technique: |
antibodies |