| Long name: |
FITC Conjugated, Pan FOXD Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FOXD |
| Specificity: |
2, 3 and 4, This antibody is useful for detecting the total expression level FOXD1, This is a highly specific antibody against FOXD |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
140-190/465 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human FOXD1 |
| Gene ID number: |
2297, 2298, 2306, 27022 |
| Swiss Prot: |
Q16676 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also acts as a transcriptional activator, Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor, Can neuralize ectodermal cells directly By similarity, Deficiency of FOXD1 results in multiorgan systemic inflammation, Deletion of FOXD1 results in renal abnormalities, FOXD1 controls the production of signals required for the normal transition of induced mesenchyme into tubular epithelium and full growth and branching of the collecting system, FOXD1 is involved in regulating inflammation as well as kidney and retinal development, FOXD1 regulates the activity of NFAT and NFkB, FOXD2 acts as a modulator of T cell activation, In kidneys, Probable transcription factor involved in embryogenesis and somatogenesis, Promotes development of neural crest cells from neural tube progenitors, Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis, Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation, and T cell proliferation in autogolgous MLRs, exaggerated Th cell-derived cytokine production, regionalization of the optic chiasm and morphogenesis of the kidney, Transcription factor required for formation of positional identity in the developing retina |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
FOXD1Forkhead box protein D4, FOXD3, FREAC-4Forkhead box protein D2, FREAC-5, FREAC-9, Forkhead-related protein FKHL17, Forkhead-related protein FKHL8, Forkhead-related protein FKHL9, Forkhead-related transcription factor 4, Forkhead-related transcription factor 5, Forkhead-related transcription factor 9, HNF3/FH transcription factor genesis, Forkhead box protein D1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Pan FOXD Conjugated |
| Short name: |
FITC Conjugated, Pan FOXD Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Pan FOXD (Antibody to) |
| Alternative technique: |
antibodies |