| Long name: |
Pan FOXD Primary Polyclonal Antibody |
| Also known as: |
Pan FOXD PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
FOXD |
| Specificity: |
2, 3 and 4, This antibody is useful for detecting the total expression level FOXD1, This is a highly specific antibody against FOXD |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
140-190/465 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FOXD1 |
| Gene ID number: |
2297, 2298, 2306, 27022 |
| Swiss Prot: |
Q16676 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Also acts as a transcriptional activator, Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor, Can neuralize ectodermal cells directly By similarity, Deficiency of FOXD1 results in multiorgan systemic inflammation, Deletion of FOXD1 results in renal abnormalities, FOXD1 controls the production of signals required for the normal transition of induced mesenchyme into tubular epithelium and full growth and branching of the collecting system, FOXD1 is involved in regulating inflammation as well as kidney and retinal development, FOXD1 regulates the activity of NFAT and NFkB, FOXD2 acts as a modulator of T cell activation, In kidneys, Probable transcription factor involved in embryogenesis and somatogenesis, Promotes development of neural crest cells from neural tube progenitors, Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis, Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation, and T cell proliferation in autogolgous MLRs, exaggerated Th cell-derived cytokine production, regionalization of the optic chiasm and morphogenesis of the kidney, Transcription factor required for formation of positional identity in the developing retina |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FOXD1Forkhead box protein D4, FOXD3, FREAC-4Forkhead box protein D2, FREAC-5, FREAC-9, Forkhead-related protein FKHL17, Forkhead-related protein FKHL8, Forkhead-related protein FKHL9, Forkhead-related transcription factor 4, Forkhead-related transcription factor 5, Forkhead-related transcription factor 9, HNF3/FH transcription factor genesis, Forkhead box protein D1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Pan FOXD |
| Short name: |
Pan FOXD Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Pan FOXD (Antibody to) |
| Alternative technique: |
antibodies |