| Catalog number: | bs-6425R-Cy5.5 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | TRP12 Antibody, Cy5.5 Conjugated |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | Cy5, 5 Conjugated, TRP12 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Cy5, 5, 5, Cy5 |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | TRP12 |
| Specificity: | This is a highly specific antibody against TRP12 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen_range: | 310-360/871 |
| Subcellular location: | Cytoplasm |
| Source: | KLH conjugated synthetic peptide derived from human TRPV4 |
| Gene ID number: | 59341 |
| Swiss Prot: | Q9HBA0 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification, Acts as a regulator of intracellular Ca(2+) in synoviocytes, Also activated by low pH, Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism, Increase of intracellular Ca(2+) potentiates currents, Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12, Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers, citrate and phorbol esters, 13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8, Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 675nm/694nm |
| Synonyms: | OTRPC4 TRP12 VROAC VRL-2 VR-OAC CMT2C |
| Properties: | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: | TRP12 Conjugated |
| Short name: | Conjugated, TRP12 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | 5, Cy5 |
| Alternative name: | cyanine 5, 5 coupled, TRP12 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 18083 |
| Gene: | TRPV4 | More about : TRPV4 |
| Long gene name: | transient receptor potential cation channel subfamily V member 4 |
| Synonyms gene name: | member 4 , subfamily V, transient receptor potential cation channel |
| Synonyms name: | osmosensitive transient receptor potential channel 4 |
| Locus: | 12q24, 11 |
| Discovery year: | 2002-01-29 |
| GenBank acession: | AF263523 |
| Entrez gene record: | 59341 |
| Pubmed identfication: | 11025659 11081638 16382100 20037587 |
| RefSeq identity: | NM_021625 |
| Classification: | Ankyrin repeat domain containing Transient receptor potential cation channels |
| Havana BLAST/BLAT: | OTTHUMG00000169277 |
| Locus Specific Databases: | LRG_372 |
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