| Catalog number: | bs-6425R-A555 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | TRP12 Antibody, ALEXA FLUOR 555 |
| Quantity: | 100ul |
| Related search: |
| Long name: | ALEXA FLUOR 555 Conjugated, TRP12 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-TRP12 PAb ALEXA FLUOR 555 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 555, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | TRP12 |
| Specificity: | This is a highly specific antibody against TRP12 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 310-360/871 |
| Subcellular location: | Cytoplasm |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRPV4 |
| Gene ID Number: | 59341 |
| Swiss Prot: | Q9HBA0 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification, Acts as a regulator of intracellular Ca(2+) in synoviocytes, Also activated by low pH, Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism, Increase of intracellular Ca(2+) potentiates currents, Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12, Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers, citrate and phorbol esters, 13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8, Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 553nm/568nm |
| Synonyms: | OTRPC4 TRP12 VROAC VRL-2 VR-OAC CMT2C |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 555, Alexa Fluor |
| Gene target: | TRP12 |
| Short name: | TRP12 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 555 |
| Alternative name: | ALEXA FLUOR 555, TRP12 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 18083 |
| Gene: | TRPV4 | More about : TRPV4 |
| Long gene name: | transient receptor potential cation channel subfamily V member 4 |
| Synonyms gene name: | member 4 , subfamily V, transient receptor potential cation channel |
| Synonyms name: | osmosensitive transient receptor potential channel 4 |
| Locus: | 12q24, 11 |
| Discovery year: | 2002-01-29 |
| GenBank acession: | AF263523 |
| Entrez gene record: | 59341 |
| Pubmed identfication: | 11025659 11081638 16382100 20037587 |
| RefSeq identity: | NM_021625 |
| Classification: | Ankyrin repeat domain containing Transient receptor potential cation channels |
| Havana BLAST/BLAT: | OTTHUMG00000169277 |
| Locus Specific Databases: | LRG_372 |
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