| Long name: |
ALEXA FLUOR 647 Conjugated, TRP12 Polyclonal Antibody |
| Also known as: |
Anti-TRP12 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TRP12 |
| Specificity: |
This is a highly specific antibody against TRP12 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
310-360/871 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRPV4 |
| Gene ID Number: |
59341 |
| Swiss Prot: |
Q9HBA0 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification, Acts as a regulator of intracellular Ca(2+) in synoviocytes, Also activated by low pH, Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism, Increase of intracellular Ca(2+) potentiates currents, Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12, Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers, citrate and phorbol esters, 13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8, Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
OTRPC4 TRP12 VROAC VRL-2 VR-OAC CMT2C |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the TRP12 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
TRP12 |
| Short name: |
TRP12 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, TRP12 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18083 |
| Gene: |
TRPV4 |
More about : TRPV4 |
| Long gene name: |
transient receptor potential cation channel subfamily V member 4 |
| Synonyms gene name: |
member 4 , subfamily V, transient receptor potential cation channel |
| Synonyms name: |
osmosensitive transient receptor potential channel 4 |
| Locus: |
12q24, 11 |
| Discovery year: |
2002-01-29 |
| GenBank acession: |
AF263523 |
| Entrez gene record: |
59341 |
| Pubmed identfication: |
11025659 11081638 16382100 20037587 |
| RefSeq identity: |
NM_021625 |
| Classification: |
Ankyrin repeat domain containing Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000169277 |
| Locus Specific Databases: |
LRG_372 |