| Long name: |
Cy5, 15 Lipoxygenase 1 Polyclonal Antibody, 5 Conjugated |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
15 Lipoxygenase 1 |
| Specificity: |
This is a highly specific antibody against 15 Lipoxygenase 1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
610-662/662 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human ALOX15/15 Lipoxygenase 1 |
| Gene ID number: |
246 |
| Swiss Prot: |
P16050 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid, Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE, Finally, In addition to its role in the immune and inflammatory responses, In parallel, May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3, May also play a role in endoplasmic reticulum stress response and the regulation of bone mass, May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway, Probably plays an important role in the immune and inflammatory responses, Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes, including macrophage function, it is also involved in the cellular response to IL13/interleukin-13, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4, may regulate actin polymerization which is crucial for several biological processes, Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
12/15-lipoxygenase, 15-LOX, 15-LOX-1, 15LOX-1, ALOX15, Arachidonate 12-lipoxygenase, Arachidonate 15-lipoxygenase, Arachidonate omega-6 lipoxygenase, LOG15, leukocyte-type, 12-LOX |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
15 Lipoxygenase 1 Conjugated |
| Short name: |
Conjugated, 15 Lipoxygenase 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 15 Lipoxygenase 1 (Antibody to), 5 coupled |
| Alternative technique: |
antibodies |