PLK1 (Ser137) Antibody, Biotin Conjugated

Catalog number:	bs-3345R-Biotin Buy Now
Price:	597 €
Supplier:	MBS Polyclonals_1
Product name:	PLK1 (Ser137) Antibody, Biotin Conjugated
Quantity:	0.05 ml
Related search:	plk antibody ser gene biotin phosphorylation kinase polo important

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Long name:	Biotin Conjugated, PLK1 (Ser137) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	PLK1 Ser137
Specificity:	This phosphorylation site is homologous across the listed species, This is a highly specific antibody against PLK1 Ser137
Modification:	Phosphorylation
Modification site:	Ser137
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	110-160/603
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human PLK1 around the phosphorylation site of Ser137
Gene ID number:	5347
Swiss Prot:	P53350
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Contributes to the regulation of AURKA function, NEDD1 phosphorylation promotes subsequent targeting of the gamma-tubulin ring complex (gTuRC) to the centrosome, Phosphorylates BORA, Phosphorylates NEDD1, Phosphorylates SGOL1, Phosphorylates both ECT2 and RACGAP1, Promotes the central spindle recruitment of ECT2, Regulates TP53 stability through phosphorylation of TOPORS, Required for kinetochore localization of BUB1B, Required for recovery after DNA damage checkpoint and entry into mitosis, Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function, an important step for spindle formation, and the regulation of mitotic exit and cytokinesis, and thereby promotes the degradation of BORA, and thereby stimulates their interaction that is essential for the cleavage furrow formation, including the regulation of centrosome maturation and spindle assembly, the inactivation of APC/C inhibitors, the removal of cohesins from chromosome arms, Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	PLK1 (Ser137) Conjugated
Short name:	Conjugated, PLK1 (Ser137) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, PLK1 (Ser137) (Antibody to)
Alternative technique:	antibodies
Identity:	9077
Gene:	PLK1 | More about : PLK1
Long gene name:	polo like kinase 1
Synonyms gene:	PLK
Synonyms gene name:	polo-like kinase (Drosophila) polo-like kinase 1
Locus:	16p12, 2
Discovery year:	1994-07-25
Entrez gene record:	5347
Pubmed identfication:	8127874
RefSeq identity:	NM_005030
Havana BLAST/BLAT:	OTTHUMG00000096984

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