PLK1 (Ser137) Antibody, ALEXA FLUOR 488

Catalog number:	bs-3345R-A488 Buy Now
Price:	597 €
Supplier:	MBS Polyclonals_1
Product name:	PLK1 (Ser137) Antibody, ALEXA FLUOR 488
Quantity:	0.05 ml
Related search:	plk ser antibody fluor gene antibodies conjugated kinase polo localization

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Long name:	ALEXA FLUOR 488 Conjugated, PLK1 (Ser137) Polyclonal Antibody
Also known as:	Anti-PLK1 Ser137 PAb ALEXA FLUOR 488
Category:	Conjugated Primary Antibodies
Conjugated with:	488, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	PLK1 Ser137
Specificity:	This is a highly specific antibody against PLK1 Ser137
Modification:	Phosphorylation
Modification Site:	Ser137
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	110-160/603
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human PLK1 around the phosphorylation site of Ser137
Gene ID Number:	5347
Swiss Prot:	P53350
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Contributes to the regulation of AURKA function, NEDD1 phosphorylation promotes subsequent targeting of the gamma-tubulin ring complex (gTuRC) to the centrosome, Phosphorylates BORA, Phosphorylates NEDD1, Phosphorylates SGOL1, Phosphorylates both ECT2 and RACGAP1, Promotes the central spindle recruitment of ECT2, Regulates TP53 stability through phosphorylation of TOPORS, Required for kinetochore localization of BUB1B, Required for recovery after DNA damage checkpoint and entry into mitosis, Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function, an important step for spindle formation, and the regulation of mitotic exit and cytokinesis, and thereby promotes the degradation of BORA, and thereby stimulates their interaction that is essential for the cleavage furrow formation, including the regulation of centrosome maturation and spindle assembly, the inactivation of APC/C inhibitors, the removal of cohesins from chromosome arms, Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	499nm/519nm
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PLK1 (Ser137) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Gene target:	PLK1 (Ser137)
Short name:	PLK1 (Ser137) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 488
Alternative name:	ALEXA FLUOR 488, PLK1 (Ser137) (Antibody to)
Alternative technique:	antibodies
Identity:	9077
Gene:	PLK1 | More about : PLK1
Long gene name:	polo like kinase 1
Synonyms gene:	PLK
Synonyms gene name:	polo-like kinase (Drosophila) polo-like kinase 1
Locus:	16p12, 2
Discovery year:	1994-07-25
Entrez gene record:	5347
Pubmed identfication:	8127874
RefSeq identity:	NM_005030
Havana BLAST/BLAT:	OTTHUMG00000096984

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