FHIT (Tyr114) Antibody, FITC Conjugated

Catalog number:	bs-3146R-FITC Buy Now
Price:	311 €
Supplier:	acr
Product name:	FHIT (Tyr114) Antibody, FITC Conjugated
Quantity:	0,1 ml
Related search:	antibody fhit antibodies tyr gene primary fluorescent storage

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Long name:	FITC Conjugated, FHIT (Tyr114) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Anti-FITC Antibody
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	FHIT Tyr114
Specificity:	This is a highly specific antibody against FHIT Tyr114
Modification:	Phosphorylation
Modification site:	Tyr114
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	90-130/147
Subcellular location:	Mitochondrion, Nucleus, Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human FHIT around the phosphorylation site of Tyr114
Gene ID number:	2272
Swiss Prot:	P49789
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), Functions as tumor suppressor, Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds, Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis, Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways, but does not require its catalytic activity, but has extremely low activity with ATP, enhancing mitochondrial calcium uptake, it may in part come from the mitochondrial form, such as CCND1 and BIRC5, which sensitizes the low-affinity Ca(2+) transporters, Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	494nm/518nm
Synonyms:	FRA3B AP3Aase
Properties:	Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	FHIT (Tyr114) Conjugated
Short name:	FITC Conjugated, FHIT (Tyr114) Antibody
Technique:	Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	FITC
Alternative name:	fluorecein coupled, FHIT (Tyr114) (Antibody to)
Alternative technique:	antibodies
Identity:	3701
Gene:	FHIT | More about : FHIT
Long gene name:	fragile histidine triad
Synonyms gene name:	fragile histidine triad gene
Locus:	3p14, 2
Discovery year:	1996-10-18
GenBank acession:	BC032336
Entrez gene record:	2272
Pubmed identfication:	8598045 9671749 26181368
RefSeq identity:	NM_002012
Havana BLAST/BLAT:	OTTHUMG00000158591

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