FHIT (Tyr114) Antibody, ALEXA FLUOR 555

Catalog number:	bs-3146R-A555 Buy Now
Price:	347 €
Supplier:	acr
Product name:	FHIT (Tyr114) Antibody, ALEXA FLUOR 555
Quantity:	50 Вµg
Related search:	fhit tyr gene antibodies conjugated apoptosis short

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Long name:	ALEXA FLUOR 555 Conjugated, FHIT (Tyr114) Polyclonal Antibody
Also known as:	Anti-FHIT Tyr114 PAb ALEXA FLUOR 555
Category:	Conjugated Primary Antibodies
Conjugated with:	555, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	FHIT Tyr114
Specificity:	This is a highly specific antibody against FHIT Tyr114
Modification:	Phosphorylation
Modification Site:	Tyr114
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	90-130/147
Subcellular location:	Mitochondrion, Nucleus, Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human FHIT around the phosphorylation site of Tyr114
Gene ID Number:	2272
Swiss Prot:	P49789
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), Functions as tumor suppressor, Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds, Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis, Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways, but does not require its catalytic activity, but has extremely low activity with ATP, enhancing mitochondrial calcium uptake, it may in part come from the mitochondrial form, such as CCND1 and BIRC5, which sensitizes the low-affinity Ca(2+) transporters, Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	553nm/568nm
Synonyms:	FRA3B AP3Aase
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 555, Alexa Fluor
Gene target:	FHIT (Tyr114)
Short name:	FHIT (Tyr114) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 555
Alternative name:	ALEXA FLUOR 555, FHIT (Tyr114) (Antibody to)
Alternative technique:	antibodies
Identity:	3701
Gene:	FHIT | More about : FHIT
Long gene name:	fragile histidine triad
Synonyms gene name:	fragile histidine triad gene
Locus:	3p14, 2
Discovery year:	1996-10-18
GenBank acession:	BC032336
Entrez gene record:	2272
Pubmed identfication:	8598045 9671749 26181368
RefSeq identity:	NM_002012
Havana BLAST/BLAT:	OTTHUMG00000158591

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