| Long name: |
Biotin Conjugated, ASPP1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ASPP1 |
| Specificity: |
This is a highly specific antibody against ASPP1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human ASPP1 |
| Gene ID number: |
23368 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
53BP2, Alternate Names: apoptosis stimulating protein of P53 1, Apoptosis-stimulating of p53 protein 2, Bbp, Bcl2-binding protein, NFKap B-interacting protein 1, PPP1R13L) is the third member of the ASPP family of proteins, RelA-associated inhibitor (RAI), Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, Unlike ASPP1 and ASPP2, and acts as an efficient inhibitor of HIV-1 gene expression in which both NFKap b and Sp1 play major roles, and gene overexpression may play an important role in the leukemogenesis and/or progression of acute leukemia, iASPP expression is upregulated in human breast carcinomas expressing wild-type p53, iASPP has been identified in a yeast-two hybrid screen as an interacting protein of the p65 subunit of NFKap B (RelA), iASPP inhibits apoptosis induced by p53 overexpression, p53-binding protein 2, p53BP2, protein phosphatase 1 regulatory subunit 13-like, which interact with p53 and enhance its ability to induce apoptosis, 3 interacts with NFKap B in vivo, iASPP (inhibitor of apoptosis stimulating protein of p53 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
p53BP2-like KIAA0771 p85 ASPP1 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ASPP1 Conjugated |
| Short name: |
Conjugated, ASPP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, ASPP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14950 |
| Gene: |
PPP1R13B |
More about : PPP1R13B |
| Long gene name: |
protein phosphatase 1 regulatory subunit 13B |
| Synonyms gene name: |
protein phosphatase 1, regulatory (inhibitor) subunit 13B protein phosphatase 1, regulatory subunit 13B |
| Locus: |
14q32, 33 |
| Discovery year: |
2001-06-29 |
| GenBank acession: |
AB018314 |
| Entrez gene record: |
23368 |
| Pubmed identfication: |
9872452 |
| RefSeq identity: |
NM_015316 |
| Classification: |
Ankyrin repeat domain containing Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000171647 |