| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ASPP1 |
| Specificity: |
This antibody reacts specifically with ASPP1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ASPP1 |
| Gene ID: |
23368 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
53BP2, Alternate Names: apoptosis stimulating protein of P53 1, Apoptosis-stimulating of p53 protein 2, Bbp, Bcl2-binding protein, NFKap B-interacting protein 1, PPP1R13L) is the third member of the ASPP family of proteins, RelA-associated inhibitor (RAI), Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, Unlike ASPP1 and ASPP2, and acts as an efficient inhibitor of HIV-1 gene expression in which both NFKap b and Sp1 play major roles, and gene overexpression may play an important role in the leukemogenesis and/or progression of acute leukemia, iASPP expression is upregulated in human breast carcinomas expressing wild-type p53, iASPP has been identified in a yeast-two hybrid screen as an interacting protein of the p65 subunit of NFKap B (RelA), iASPP inhibits apoptosis induced by p53 overexpression, p53-binding protein 2, p53BP2, protein phosphatase 1 regulatory subunit 13-like, which interact with p53 and enhance its ability to induce apoptosis, 3 interacts with NFKap B in vivo, iASPP (inhibitor of apoptosis stimulating protein of p53 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
p53BP2-like KIAA0771 p85 ASPP1 |
| Also known as: |
ASPP1 Polyclonal Antibody |
| Other name: |
Anti-ASPP1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ASPP1 |
| Short name: |
Anti-ASPP1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ASPP1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
14950 |
| Gene: |
PPP1R13B |
More about : PPP1R13B |
| Long gene name: |
protein phosphatase 1 regulatory subunit 13B |
| Synonyms gene name: |
protein phosphatase 1, regulatory (inhibitor) subunit 13B protein phosphatase 1, regulatory subunit 13B |
| Locus: |
14q32, 33 |
| Discovery year: |
2001-06-29 |
| GenBank acession: |
AB018314 |
| Entrez gene record: |
23368 |
| Pubmed identfication: |
9872452 |
| RefSeq identity: |
NM_015316 |
| Classification: |
Ankyrin repeat domain containing Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000171647 |