| Long name: |
ASPP1 Primary Polyclonal Antibody |
| Also known as: |
ASPP1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ASPP1 |
| Specificity: |
This is a highly specific antibody against ASPP1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ASPP1 |
| Gene ID number: |
23368 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
53BP2, Alternate Names: apoptosis stimulating protein of P53 1, Apoptosis-stimulating of p53 protein 2, Bbp, Bcl2-binding protein, NFKap B-interacting protein 1, PPP1R13L) is the third member of the ASPP family of proteins, RelA-associated inhibitor (RAI), Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, Unlike ASPP1 and ASPP2, and acts as an efficient inhibitor of HIV-1 gene expression in which both NFKap b and Sp1 play major roles, and gene overexpression may play an important role in the leukemogenesis and/or progression of acute leukemia, iASPP expression is upregulated in human breast carcinomas expressing wild-type p53, iASPP has been identified in a yeast-two hybrid screen as an interacting protein of the p65 subunit of NFKap B (RelA), iASPP inhibits apoptosis induced by p53 overexpression, p53-binding protein 2, p53BP2, protein phosphatase 1 regulatory subunit 13-like, which interact with p53 and enhance its ability to induce apoptosis, 3 interacts with NFKap B in vivo, iASPP (inhibitor of apoptosis stimulating protein of p53 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
53BP2, Apoptosis-stimulating of p53 protein 2, Bbp, Bcl2-binding protein, PPP1R13B, Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, apoptosis stimulating protein of P53 1, p53-binding protein 2, p53BP2, p85, p53BP2 like |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ASPP1 |
| Short name: |
ASPP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ASPP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14950 |
| Gene: |
PPP1R13B |
More about : PPP1R13B |
| Long gene name: |
protein phosphatase 1 regulatory subunit 13B |
| Synonyms gene name: |
protein phosphatase 1, regulatory (inhibitor) subunit 13B protein phosphatase 1, regulatory subunit 13B |
| Synonyms: |
p53BP2-like KIAA0771 p85 ASPP1 |
| Locus: |
14q32, 33 |
| Discovery year: |
2001-06-29 |
| GenBank acession: |
AB018314 |
| Entrez gene record: |
23368 |
| Pubmed identfication: |
9872452 |
| RefSeq identity: |
NM_015316 |
| Classification: |
Ankyrin repeat domain containing Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000171647 |