| Long name: |
ALEXA FLUOR 647 Conjugated, ASPP1 Polyclonal Antibody |
| Also known as: |
Anti-ASPP1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ASPP1 |
| Specificity: |
This is a highly specific antibody against ASPP1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ASPP1 |
| Gene ID Number: |
23368 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
53BP2, Alternate Names: apoptosis stimulating protein of P53 1, Apoptosis-stimulating of p53 protein 2, Bbp, Bcl2-binding protein, NFKap B-interacting protein 1, PPP1R13L) is the third member of the ASPP family of proteins, RelA-associated inhibitor (RAI), Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, Unlike ASPP1 and ASPP2, and acts as an efficient inhibitor of HIV-1 gene expression in which both NFKap b and Sp1 play major roles, and gene overexpression may play an important role in the leukemogenesis and/or progression of acute leukemia, iASPP expression is upregulated in human breast carcinomas expressing wild-type p53, iASPP has been identified in a yeast-two hybrid screen as an interacting protein of the p65 subunit of NFKap B (RelA), iASPP inhibits apoptosis induced by p53 overexpression, p53-binding protein 2, p53BP2, protein phosphatase 1 regulatory subunit 13-like, which interact with p53 and enhance its ability to induce apoptosis, 3 interacts with NFKap B in vivo, iASPP (inhibitor of apoptosis stimulating protein of p53 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
p53BP2-like KIAA0771 p85 ASPP1 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the ASPP1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
ASPP1 |
| Short name: |
ASPP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, ASPP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14950 |
| Gene: |
PPP1R13B |
More about : PPP1R13B |
| Long gene name: |
protein phosphatase 1 regulatory subunit 13B |
| Synonyms gene name: |
protein phosphatase 1, regulatory (inhibitor) subunit 13B protein phosphatase 1, regulatory subunit 13B |
| Locus: |
14q32, 33 |
| Discovery year: |
2001-06-29 |
| GenBank acession: |
AB018314 |
| Entrez gene record: |
23368 |
| Pubmed identfication: |
9872452 |
| RefSeq identity: |
NM_015316 |
| Classification: |
Ankyrin repeat domain containing Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000171647 |