| Catalog number: | bs-1282R-A350 |
|---|---|
| Price: | 332 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | ASPP1 Antibody, ALEXA FLUOR 350 |
| Quantity: | 100ul |
| Related search: |
| Long name: | ALEXA FLUOR 350 Conjugated, ASPP1 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-ASPP1 PAb ALEXA FLUOR 350 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 350, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | ASPP1 |
| Specificity: | This is a highly specific antibody against ASPP1 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ASPP1 |
| Gene ID Number: | 23368 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | 53BP2, Alternate Names: apoptosis stimulating protein of P53 1, Apoptosis-stimulating of p53 protein 2, Bbp, Bcl2-binding protein, NFKap B-interacting protein 1, PPP1R13L) is the third member of the ASPP family of proteins, RelA-associated inhibitor (RAI), Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, Unlike ASPP1 and ASPP2, and acts as an efficient inhibitor of HIV-1 gene expression in which both NFKap b and Sp1 play major roles, and gene overexpression may play an important role in the leukemogenesis and/or progression of acute leukemia, iASPP expression is upregulated in human breast carcinomas expressing wild-type p53, iASPP has been identified in a yeast-two hybrid screen as an interacting protein of the p65 subunit of NFKap B (RelA), iASPP inhibits apoptosis induced by p53 overexpression, p53-binding protein 2, p53BP2, protein phosphatase 1 regulatory subunit 13-like, which interact with p53 and enhance its ability to induce apoptosis, 3 interacts with NFKap B in vivo, iASPP (inhibitor of apoptosis stimulating protein of p53 |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 343nm/442nm |
| Synonyms: | p53BP2-like KIAA0771 p85 ASPP1 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 350, Alexa Fluor |
| Gene target: | ASPP1 |
| Short name: | ASPP1 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 350 |
| Alternative name: | ALEXA FLUOR 350, ASPP1 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 14950 |
| Gene: | PPP1R13B | More about : PPP1R13B |
| Long gene name: | protein phosphatase 1 regulatory subunit 13B |
| Synonyms gene name: | protein phosphatase 1, regulatory (inhibitor) subunit 13B protein phosphatase 1, regulatory subunit 13B |
| Locus: | 14q32, 33 |
| Discovery year: | 2001-06-29 |
| GenBank acession: | AB018314 |
| Entrez gene record: | 23368 |
| Pubmed identfication: | 9872452 |
| RefSeq identity: | NM_015316 |
| Classification: | Ankyrin repeat domain containing Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: | OTTHUMG00000171647 |
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