ATF1 (Ser63) Antibody, ALEXA FLUOR 594

Catalog number:	bs-12535R-A594 Buy Now
Price:	384 €
Supplier:	acr
Product name:	ATF1 (Ser63) Antibody, ALEXA FLUOR 594
Quantity:	50 Вµl
Related search:	atf alexa ser antibody antibodies gene proteins phosphorylation treb

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Long name:	ALEXA FLUOR 594 Conjugated, ATF1 (Ser63) Polyclonal Antibody
Also known as:	Anti-ATF1 Ser63 PAb ALEXA FLUOR 594
Category:	Conjugated Primary Antibodies
Conjugated with:	594, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	ATF1 Ser63
Specificity:	This is a highly specific antibody against ATF1 Ser63
Modification:	Phosphorylation
Modification Site:	Ser63
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human ATF1 around the phosphorylation site of Ser63
Gene ID Number:	466
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	A chimeric protein composed of the N-terminal domain of EWS (Ewing sarcoma oncogene) linked to the bZip domain of ATF1 is implicated in the rare malignant clear cell sarcoma of tendon sheath and aponeuroses (malignant melanoma of soft parts), ATF1 is a nuclear protein that binds DNA as a homodimer or as heterodimers with the inducible transcription factors CREB1 or CREM, ATF1 is detectable in metastatic melanoma cells and seems to contribute to their survival, ATF1 mediates both Ca2+ and cAMP responses at several levels, Heterodimers appear to be stronger transcriptional activators than the homodimers, It binds to the Tax-responsive element (TRE1) of the human T-cell lymphotropic virus type-I (HTLV1), Many of these genes are important in cell growth and differentiation, Several isoforms of ATF1 arise by differential splicing, TREB-36) is a member of the ATF/CREB family of basic region leucine-zipper (bZip) DNA-binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes, The activation function of CRE-binding proteins may be modulated by phosphorylation of several kinases and is mediated by coactivators such as CREB-binding protein (CBP) and p300, Tissue expression of ATF1 mRNA is widespread, and in stress and immune responses, ATF1 (Activating Transcription Factor 1
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	590nm/617nm
Synonyms:	TREB36
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	594, ALEXA FLUOR®, Alexa Fluor
Conjugated:	Alexa conjugate 1
Gene target:	ATF1 (Ser63)
Short name:	ATF1 (Ser63) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 594
Alternative name:	ALEXA FLUOR 594, ATF1 (Ser63) (Antibody to)
Alternative technique:	antibodies
Identity:	783
Gene:	ATF1 | More about : ATF1
Long gene name:	activating transcription factor 1
Locus:	12q13, 12
Discovery year:	1994-03-16
GenBank acession:	BC029619
Entrez gene record:	466
Pubmed identfication:	8401579
RefSeq identity:	NM_005171
Classification:	Basic leucine zipper proteins
Havana BLAST/BLAT:	OTTHUMG00000169482

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