ATF1 (Ser63) Antibody, FITC Conjugated

Catalog number:	bs-12535R-FITC Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	ATF1 (Ser63) Antibody, FITC Conjugated
Quantity:	0.1ml
Related search:	atf antibody antibodies ser gene proteins fluorescent heterodimers

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Long name:	FITC Conjugated, ATF1 (Ser63) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Anti-FITC Antibody
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	ATF1 Ser63
Specificity:	This is a highly specific antibody against ATF1 Ser63
Modification:	Phosphorylation
Modification site:	Ser63
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human ATF1 around the phosphorylation site of Ser63
Gene ID number:	466
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	A chimeric protein composed of the N-terminal domain of EWS (Ewing sarcoma oncogene) linked to the bZip domain of ATF1 is implicated in the rare malignant clear cell sarcoma of tendon sheath and aponeuroses (malignant melanoma of soft parts), ATF1 is a nuclear protein that binds DNA as a homodimer or as heterodimers with the inducible transcription factors CREB1 or CREM, ATF1 is detectable in metastatic melanoma cells and seems to contribute to their survival, ATF1 mediates both Ca2+ and cAMP responses at several levels, Heterodimers appear to be stronger transcriptional activators than the homodimers, It binds to the Tax-responsive element (TRE1) of the human T-cell lymphotropic virus type-I (HTLV1), Many of these genes are important in cell growth and differentiation, Several isoforms of ATF1 arise by differential splicing, TREB-36) is a member of the ATF/CREB family of basic region leucine-zipper (bZip) DNA-binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes, The activation function of CRE-binding proteins may be modulated by phosphorylation of several kinases and is mediated by coactivators such as CREB-binding protein (CBP) and p300, Tissue expression of ATF1 mRNA is widespread, and in stress and immune responses, ATF1 (Activating Transcription Factor 1
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	494nm/518nm
Synonyms:	TREB36
Properties:	Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	ATF1 (Ser63) Conjugated
Short name:	FITC Conjugated, ATF1 (Ser63) Antibody
Technique:	Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	FITC
Alternative name:	fluorecein coupled, ATF1 (Ser63) (Antibody to)
Alternative technique:	antibodies
Identity:	783
Gene:	ATF1 | More about : ATF1
Long gene name:	activating transcription factor 1
Locus:	12q13, 12
Discovery year:	1994-03-16
GenBank acession:	BC029619
Entrez gene record:	466
Pubmed identfication:	8401579
RefSeq identity:	NM_005171
Classification:	Basic leucine zipper proteins
Havana BLAST/BLAT:	OTTHUMG00000169482

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