| Long name: |
ALEXA FLUOR 350 Conjugated, CSEN (Ser63) Polyclonal Antibody |
| Also known as: |
Anti-CSEN Ser63 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CSEN Ser63 |
| Specificity: |
This is a highly specific antibody against CSEN Ser63 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser63 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Membrane bound |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human CSEN around the phosphorylation site of Ser63 |
| Gene ID Number: |
30818 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
DRE is a regulatory sequence that silences basal transcription and is localized to the promoter region of the gene encoding human prodynorphin, DREAM forms functional homotetramers that are required for the interaction with the DRE, DREAM has been shown to inhibit transcription of other proteins containing DRE-like motifs, DREAM transcripts are detected in brain, This association is highly influenced by calcium, an opioid peptide involved in memory acquisition and pain, and it is expressed as a nuclear protein, as an increase in Ca2+ directly inhibits DREAM binding and thereby blocks the repressor activity of DREAM, including the gene encoding for the AP-1 transcription factor c-Fos, suggesting that DREAM may influence a wide variety of cellular genes, thymus and thyroid gland, CSEN is a Ca2+-regulated transcriptional repressor that specifically binds to the downstream regulatory elements (DRE) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
DREAM KCHIP3 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
CSEN (Ser63) |
| Short name: |
CSEN (Ser63) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, CSEN (Ser63) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
15523 |
| Gene: |
KCNIP3 |
More about : KCNIP3 |
| Long gene name: |
potassium voltage-gated channel interacting protein 3 |
| Synonyms gene: |
CSEN |
| Synonyms gene name: |
EF hand transcription factor Kv channel interacting protein 3, calsenilin, calsenilin , presenilin-binding protein |
| Synonyms name: |
calsenilin |
| Locus: |
2q11, 1 |
| Discovery year: |
2001-05-24 |
| GenBank acession: |
AF199599 |
| Entrez gene record: |
30818 |
| Pubmed identfication: |
9771752 10078534 |
| RefSeq identity: |
NM_013434 |
| Classification: |
Potassium voltage-gated channel regulatory subunits EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130392 |