CSEN (Ser63) Antibody, ALEXA FLUOR 555

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Catalog number: bs-12167R-A555
Price: 516 €
Supplier: Bioss Polyclonal Antibodies
Product name: CSEN (Ser63) Antibody, ALEXA FLUOR 555
Quantity: 100 microliters
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Long name: ALEXA FLUOR 555 Conjugated, CSEN (Ser63) Polyclonal Antibody
Also known as: Anti-CSEN Ser63 PAb ALEXA FLUOR 555
Category: Conjugated Primary Antibodies
Conjugated with: 555, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: CSEN Ser63
Specificity: This is a highly specific antibody against CSEN Ser63
Modification: Phosphorylation
Modification Site: Ser63
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Subcellular location: Membrane bound
Source: KLH conjugated synthetic phosphopeptide derived from human CSEN around the phosphorylation site of Ser63
Gene ID Number: 30818
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: DRE is a regulatory sequence that silences basal transcription and is localized to the promoter region of the gene encoding human prodynorphin, DREAM forms functional homotetramers that are required for the interaction with the DRE, DREAM has been shown to inhibit transcription of other proteins containing DRE-like motifs, DREAM transcripts are detected in brain, This association is highly influenced by calcium, an opioid peptide involved in memory acquisition and pain, and it is expressed as a nuclear protein, as an increase in Ca2+ directly inhibits DREAM binding and thereby blocks the repressor activity of DREAM, including the gene encoding for the AP-1 transcription factor c-Fos, suggesting that DREAM may influence a wide variety of cellular genes, thymus and thyroid gland, CSEN is a Ca2+-regulated transcriptional repressor that specifically binds to the downstream regulatory elements (DRE)
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 553nm/568nm
Synonyms: DREAM KCHIP3
Properties: ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: ALEXA FLUOR 555, Alexa Fluor
Gene target: CSEN (Ser63)
Short name: CSEN (Ser63) Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 555
Alternative name: ALEXA FLUOR 555, CSEN (Ser63) (Antibody to)
Alternative technique: antibodies
Identity: 15523
Gene: KCNIP3 | More about : KCNIP3
Long gene name: potassium voltage-gated channel interacting protein 3
Synonyms gene: CSEN
Synonyms gene name: EF hand transcription factor Kv channel interacting protein 3, calsenilin, calsenilin , presenilin-binding protein
Synonyms name: calsenilin
Locus: 2q11, 1
Discovery year: 2001-05-24
GenBank acession: AF199599
Entrez gene record: 30818
Pubmed identfication: 9771752 10078534
RefSeq identity: NM_013434
Classification: Potassium voltage-gated channel regulatory subunits EF-hand domain containing
Havana BLAST/BLAT: OTTHUMG00000130392

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