| Long name: |
Cy7 Conjugated, APPBP1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
APPBP1 |
| Specificity: |
This is a highly specific antibody against APPBP1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
440-490/534 |
| Subcellular location: |
Cell membrane |
| Source: |
KLH conjugated synthetic peptide derived from human APPBP1 |
| Gene ID number: |
8883 |
| Swiss Prot: |
Q13564 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M, Necessary for cell cycle progression through the S-M checkpoint, Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP, Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
ula-1 APP-BP1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
APPBP1 Conjugated |
| Short name: |
Conjugated, APPBP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, APPBP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
621 |
| Gene: |
NAE1 |
More about : NAE1 |
| Long gene name: |
NEDD8 activating enzyme E1 subunit 1 |
| Synonyms gene: |
APPBP1 |
| Synonyms gene name: |
59kDa , amyloid beta precursor protein binding protein 1 |
| Locus: |
16q22, 1 |
| Discovery year: |
1999-01-13 |
| GenBank acession: |
U50939 |
| Entrez gene record: |
8883 |
| Pubmed identfication: |
8626687 12740388 |
| RefSeq identity: |
NM_003905 |
| Classification: |
Ubiquitin like modifier activating enzymes |
| Havana BLAST/BLAT: |
OTTHUMG00000137513 |