| Catalog number: | bs-12503R-Cy3 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | APPBP1 Antibody, Cy3 Conjugated |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | Cy3 Conjugated, APPBP1 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | cy3 conjugation kit |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | APPBP1 |
| Specificity: | This is a highly specific antibody against APPBP1 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen_range: | 440-490/534 |
| Subcellular location: | Cell membrane |
| Source: | KLH conjugated synthetic peptide derived from human APPBP1 |
| Gene ID number: | 8883 |
| Swiss Prot: | Q13564 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M, Necessary for cell cycle progression through the S-M checkpoint, Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP, Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 512, 550nm/570, 615nm |
| Synonyms: | ula-1 APP-BP1 |
| Properties: | 1 of the APPBP1 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | APPBP1 Conjugated |
| Short name: | Conjugated, APPBP1 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Cy3 |
| Alternative name: | cyanine 3 coupled, APPBP1 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 621 |
| Gene: | NAE1 | More about : NAE1 |
| Long gene name: | NEDD8 activating enzyme E1 subunit 1 |
| Synonyms gene: | APPBP1 |
| Synonyms gene name: | 59kDa , amyloid beta precursor protein binding protein 1 |
| Locus: | 16q22, 1 |
| Discovery year: | 1999-01-13 |
| GenBank acession: | U50939 |
| Entrez gene record: | 8883 |
| Pubmed identfication: | 8626687 12740388 |
| RefSeq identity: | NM_003905 |
| Classification: | Ubiquitin like modifier activating enzymes |
| Havana BLAST/BLAT: | OTTHUMG00000137513 |
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