| Long name: |
ALEXA FLUOR 647 Conjugated, APPBP1 Polyclonal Antibody |
| Also known as: |
Anti-APPBP1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
APPBP1 |
| Specificity: |
This is a highly specific antibody against APPBP1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
440-490/534 |
| Subcellular location: |
Cell membrane |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APPBP1 |
| Gene ID Number: |
8883 |
| Swiss Prot: |
Q13564 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M, Necessary for cell cycle progression through the S-M checkpoint, Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP, Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
ula-1 APP-BP1 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the APPBP1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
APPBP1 |
| Short name: |
APPBP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, APPBP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
621 |
| Gene: |
NAE1 |
More about : NAE1 |
| Long gene name: |
NEDD8 activating enzyme E1 subunit 1 |
| Synonyms gene: |
APPBP1 |
| Synonyms gene name: |
59kDa , amyloid beta precursor protein binding protein 1 |
| Locus: |
16q22, 1 |
| Discovery year: |
1999-01-13 |
| GenBank acession: |
U50939 |
| Entrez gene record: |
8883 |
| Pubmed identfication: |
8626687 12740388 |
| RefSeq identity: |
NM_003905 |
| Classification: |
Ubiquitin like modifier activating enzymes |
| Havana BLAST/BLAT: |
OTTHUMG00000137513 |