| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
APPBP1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the APPBP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This APPBP1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
8883 |
| Purity: |
Antigen affinity |
| Description: |
APPBP1 is required for cell cycle progression through the S/M checkpoint, In addition, Three transcript variants encoding different isoforms have been found for this gene, a cell surface protein with signal-transducing properties, a ubiquitin-like protein, and it is thought to play a role in the pathogenesis of Alzheimers disease, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, Amyloid beta precursor protein binding protein 1 (APPBP1) binds to the beta-amyloid precursor protein |
| Immunogen: |
Human partial recombinant protein (AA 181-534) was used as the immunogen for this APPBP1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the APPBP1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
APPBP1 |
| Short name: |
APPBP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
APPBP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
621 |
| Gene: |
NAE1 |
More about : NAE1 |
| Long gene name: |
NEDD8 activating enzyme E1 subunit 1 |
| Synonyms gene: |
APPBP1 |
| Synonyms gene name: |
59kDa , amyloid beta precursor protein binding protein 1 |
| Synonyms: |
ula-1 APP-BP1 |
| Locus: |
16q22, 1 |
| Discovery year: |
1999-01-13 |
| GenBank acession: |
U50939 |
| Entrez gene record: |
8883 |
| Pubmed identfication: |
8626687 12740388 |
| RefSeq identity: |
NM_003905 |
| Classification: |
Ubiquitin like modifier activating enzymes |
| Havana BLAST/BLAT: |
OTTHUMG00000137513 |