| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CSEN |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the CSEN antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This CSEN antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9Y2W7 |
| Purity: |
Antigen affinity |
| Description: |
Calsenilin functions as a calcium-regulated transcriptional repressor, It has been shown to interact with PSEN1 and PSEN2, KCNIP3-regulated genes have a critical function in Ig subclass production and proliferation in B lymphocytes, The KCNIP3 gene encodes a member of the family of voltage-gated potassium(Kv) channel-interacting proteins, and immune cells, and interacts with presenilins, testis, thymus, thyroid gland, which belong to the neuronal calcium sensor family of proteins, Calsenilin (CSEN) is a calcium-dependent transcriptional repressor that is highly expressed in central nervous system |
| Immunogen: |
An amino acid sequence from the N-terminus of human Calsenilin (MQPAKEVTKASDGSLL) was used as the immunogen for this CSEN antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CSEN antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CSEN |
| Short name: |
CSEN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CSEN (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
15523 |
| Gene: |
KCNIP3 |
More about : KCNIP3 |
| Long gene name: |
potassium voltage-gated channel interacting protein 3 |
| Synonyms gene: |
CSEN |
| Synonyms gene name: |
EF hand transcription factor Kv channel interacting protein 3, calsenilin, calsenilin , presenilin-binding protein |
| Synonyms: |
DREAM KCHIP3 |
| Synonyms name: |
calsenilin |
| Locus: |
2q11, 1 |
| Discovery year: |
2001-05-24 |
| GenBank acession: |
AF199599 |
| Entrez gene record: |
30818 |
| Pubmed identfication: |
9771752 10078534 |
| RefSeq identity: |
NM_013434 |
| Classification: |
Potassium voltage-gated channel regulatory subunits EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130392 |