Spinophilin/Neurabin 2 Antibody, Biotin Conjugated

Catalog number:	bs-12146R-Biotin Buy Now
Price:	263 €
Supplier:	Bioss Primary Unconjugated Antibodies
Product name:	Spinophilin/Neurabin 2 Antibody, Biotin Conjugated
Quantity:	0.1ml
Related search:	antibody antibodies signaling receptors protein may role

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Long name:	Biotin Conjugated, Spinophilin/Neurabin 2 Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Spinophilin/Neurabin 2
Specificity:	This is a highly specific antibody against Spinophilin/Neurabin 2
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	360-410/815
Subcellular location:	Cell membrane, Nucleus, Cytoplasm
Source:	KLH conjugated synthetic peptide derived from human Spinophilin/Neurabin 2
Gene ID number:	84687
Swiss Prot:	Q96SB3
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Believed to target protein phosphatase 1/PP1 to dendritic spines, Binds along the sides of the F-actin, Binds to ADRA1B and RGS2 and mediates regulation of ADRA1B signaling, Binds to actin filaments (F-actin) and shows cross-linking activity, May confer to Rac signaling specificity by binding to both, May establish a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton, May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction, Modulates excitatory synaptic transmission and dendritic spine morphology, Plays a role in regulation of G-protein coupled receptor signaling, Probably regulates p70 S6 kinase activity by forming a complex with TIAM1 (By similarity), RacGEFs and Rac effector proteins, Required for hepatocyte growth factor (HGF)-induced cell migration, and regulates its specificity toward ion channels and other substrates, including dopamine D2 receptors and alpha-adrenergic receptors, such as AMPA-type and NMDA-type glutamate receptors, which are rich in F-actin, Seems to act as a scaffold protein in multiple signaling pathways
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms:	Neurabin-2, Neurabin-II, PPP1R6, PPP1R9, PPP1R9B, Protein phosphatase 1 regulatory subunit 9B, SPINO, Spinophilin, Spn
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	Spinophilin/Neurabin 2 Conjugated
Short name:	Conjugated, Spinophilin/Neurabin 2 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, Spinophilin/Neurabin 2 (Antibody to)
Alternative technique:	antibodies

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