Spinophilin/Neurabin 2 Antibody, ALEXA FLUOR 488

Catalog number:	bs-12146R-A488 Buy Now
Price:	333 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	Spinophilin/Neurabin 2 Antibody, ALEXA FLUOR 488
Quantity:	0.1ml
Related search:	antibody spinophilinneurabin signaling receptors protein may

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Long name:	ALEXA FLUOR 488 Conjugated, Spinophilin/Neurabin 2 Antibody
Also known as:	Anti-Spinophilin/Neurabin 2 PAb ALEXA FLUOR 488
Category:	Conjugated Primary Antibodies
Conjugated with:	488, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Spinophilin/Neurabin 2
Specificity:	This is a highly specific antibody against Spinophilin/Neurabin 2
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	360-410/815
Subcellular location:	Cell membrane, Nucleus, Cytoplasm
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Spinophilin/Neurabin 2
Gene ID Number:	84687
Swiss Prot:	Q96SB3
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Believed to target protein phosphatase 1/PP1 to dendritic spines, Binds along the sides of the F-actin, Binds to ADRA1B and RGS2 and mediates regulation of ADRA1B signaling, Binds to actin filaments (F-actin) and shows cross-linking activity, May confer to Rac signaling specificity by binding to both, May establish a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton, May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction, Modulates excitatory synaptic transmission and dendritic spine morphology, Plays a role in regulation of G-protein coupled receptor signaling, Probably regulates p70 S6 kinase activity by forming a complex with TIAM1 (By similarity), RacGEFs and Rac effector proteins, Required for hepatocyte growth factor (HGF)-induced cell migration, and regulates its specificity toward ion channels and other substrates, including dopamine D2 receptors and alpha-adrenergic receptors, such as AMPA-type and NMDA-type glutamate receptors, which are rich in F-actin, Seems to act as a scaffold protein in multiple signaling pathways
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	499nm/519nm
Synonyms:	Neurabin-2, Neurabin-II, PPP1R6, PPP1R9, PPP1R9B, Protein phosphatase 1 regulatory subunit 9B, SPINO, Spinophilin, Spn
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Spinophilin/Neurabin 2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Gene target:	Spinophilin/Neurabin 2
Short name:	Spinophilin/Neurabin 2 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 488
Alternative name:	ALEXA FLUOR 488, Spinophilin/Neurabin 2 (Antibody to)
Alternative technique:	antibodies

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