Neurabin 1/PPP1R9A Antibody, ALEXA FLUOR 594

Catalog number:	bs-11988R-A594 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	Neurabin 1/PPP1R9A Antibody, ALEXA FLUOR 594
Quantity:	0.1ml
Related search:	neurabin alexa pppra antibody protein gene regulatory properties

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Long name:	ALEXA FLUOR 594 Conjugated, Neurabin 1/PPP1R9A Polyclonal Antibody
Also known as:	Anti-Neurabin 1/PPP1R9A PAb ALEXA FLUOR 594
Category:	Conjugated Primary Antibodies
Conjugated with:	594, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Neurabin 1/PPP1R9A
Specificity:	This is a highly specific antibody against Neurabin 1/PPP1R9A
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Neurabin 1
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Neurabin I recruits active PP1 via a PP1-docking sequence, Neurabin II (Spinophilin) is ubiquitously expressed but is abundantly expressed in brain (4), Neurabin II complexes with the catalytic subunit of protein phosphatase-1 (PP1) in vitro thus modulating the activity of PP1 (4), Neurabin II localizes to neuronal dentritic spines, Neurabin II may regulate dendritic spine properties as neurabin II(-) mice have increased spine density during development in vitro and exhibit altered filopodial formation in cultured cells (5), Neurabin may also play a role in glutamatergic transmission as Neurabin II(-) mice exhibit reduced long-term depression and resistance to kainate-induced seizures and neronal apoptosis (5), Suppression of endogenous neurabin in rat hippocampal neurons inhibits neurite formation (1), it localizes in the growth cone lamellipodia during neuronal development (1), mutation of the PP1-binding motif halts filopodia and restores stress fibers in neurabin I-expressing cells (2, which are the specialized protrusions from dendritic shafts that receive most of the excitatory input in the CNS (5), 3), Brain-specific neurabin I (neural tissue-specific F-actin binding protein I) is highly concentrated in the synapse of developed neurons
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	590nm/617nm
Synonyms:	Neurabin-I KIAA1222 FLJ20068
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	594, ALEXA FLUOR®, Alexa Fluor
Conjugated:	Alexa conjugate 1
Gene target:	Neurabin 1/PPP1R9A
Short name:	Neurabin 1/PPP1R9A Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 594
Alternative name:	ALEXA FLUOR 594, Neurabin 1/PPP1R9A (Antibody to)
Alternative technique:	antibodies
Identity:	14946
Gene:	PPP1R9A | More about : PPP1R9A
Long gene name:	protein phosphatase 1 regulatory subunit 9A
Synonyms gene name:	protein phosphatase 1, regulatory (inhibitor) subunit 9A protein phosphatase 1, regulatory subunit 9A
Locus:	7q21, 3
Discovery year:	2001-06-29
GenBank acession:	AB033048
Entrez gene record:	55607
Pubmed identfication:	10574462
RefSeq identity:	NM_001166160
Classification:	Sterile alpha motif domain containing Protein phosphatase 1 regulatory subunits PDZ domain containing
Havana BLAST/BLAT:	OTTHUMG00000155566

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