SPG3A/Atlastin Antibody, Cy5.5 Conjugated

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Catalog number: bs-11759R-Cy5.5
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: SPG3A/Atlastin Antibody, Cy5.5 Conjugated
Quantity: 0.1ml
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More details :

Long name: Cy5, 5 Conjugated, SPG3A/Atlastin Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Cy5, 5, 5, Cy5
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: SPG3A/Atlastin
Specificity: This is a highly specific antibody against SPG3A/Atlastin
Modification: Unmodified
Modification site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic peptide derived from human SPG3A/Atlastin
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: HSP primarily affects long corticospinal neurons and causes spastic lower extremity weakness, Hereditary spastic paraplegia (HSP) is an inherited neurodegenerative disorder that is characterized by retrograde axonal degeneration, Mutations in the Atlastin gene (SPG3A) account for approximately 10% of all autosomal dominant HSPs, Spastin, The Atlastin proteins, This Spastin/Atlastin binding may be involved in the biochemical pathway that leads to HSP development, a microtubule (MT)-severing AAA ATPase, also designated SPG3A and guanylate-binding protein 3, comprise a Dynamin superfamily that plays a role in axonal maintenance, integral membrane proteins that function as GTPases, is a binding partner of Atlastin that is involved in membrane dynamics, while mutations in the Spastin gene (SPG4) account for almost 40%, Atlastins are Golgi-localized
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission: 675nm/694nm
Synonyms: FSP1 AD-FSP
Properties: Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated: These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene target: SPG3A/Atlastin Conjugated
Short name: Conjugated, SPG3A/Atlastin Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: 5, Cy5
Alternative name: cyanine 5, 5 coupled, SPG3A/Atlastin (Antibody to)
Alternative technique: antibodies
Identity: 11231
Gene: ATL1 | More about : ATL1
Long gene name: atlastin GTPase 1
Synonyms gene: SPG3 SPG3A
Synonyms gene name: spastic paraplegia 3A (autosomal dominant)
Synonyms name: atlastin
Locus: 14q22, 1
Discovery year: 1993-10-28
GenBank acession: AF131801
Entrez gene record: 51062
Pubmed identfication: 8252041 7825576
Havana BLAST/BLAT: OTTHUMG00000140297
Locus Specific Databases: LRG_360

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