SPG3A/Atlastin Antibody, ALEXA FLUOR 350

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Catalog number: bs-11759R-A350
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: SPG3A/Atlastin Antibody, ALEXA FLUOR 350
Quantity: 100ul
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Long name: ALEXA FLUOR 350 Conjugated, SPG3A/Atlastin Polyclonal Antibody
Also known as: Anti-SPG3A/Atlastin PAb ALEXA FLUOR 350
Category: Conjugated Primary Antibodies
Conjugated with: 350, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: SPG3A/Atlastin
Specificity: This is a highly specific antibody against SPG3A/Atlastin
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SPG3A/Atlastin
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: HSP primarily affects long corticospinal neurons and causes spastic lower extremity weakness, Hereditary spastic paraplegia (HSP) is an inherited neurodegenerative disorder that is characterized by retrograde axonal degeneration, Mutations in the Atlastin gene (SPG3A) account for approximately 10% of all autosomal dominant HSPs, Spastin, The Atlastin proteins, This Spastin/Atlastin binding may be involved in the biochemical pathway that leads to HSP development, a microtubule (MT)-severing AAA ATPase, also designated SPG3A and guanylate-binding protein 3, comprise a Dynamin superfamily that plays a role in axonal maintenance, integral membrane proteins that function as GTPases, is a binding partner of Atlastin that is involved in membrane dynamics, while mutations in the Spastin gene (SPG4) account for almost 40%, Atlastins are Golgi-localized
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 343nm/442nm
Synonyms: FSP1 AD-FSP
Properties: ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: ALEXA FLUOR 350, Alexa Fluor
Gene target: SPG3A/Atlastin
Short name: SPG3A/Atlastin Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 350
Alternative name: ALEXA FLUOR 350, SPG3A/Atlastin (Antibody to)
Alternative technique: antibodies
Identity: 11231
Gene: ATL1 | More about : ATL1
Long gene name: atlastin GTPase 1
Synonyms gene: SPG3 SPG3A
Synonyms gene name: spastic paraplegia 3A (autosomal dominant)
Synonyms name: atlastin
Locus: 14q22, 1
Discovery year: 1993-10-28
GenBank acession: AF131801
Entrez gene record: 51062
Pubmed identfication: 8252041 7825576
Havana BLAST/BLAT: OTTHUMG00000140297
Locus Specific Databases: LRG_360

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